MidSouth is a red grape that was bred in Mississippi. While it has been used to make wine, it is more often used for products like juice, jelly, or jam. The potential exists for wine production, but it may have best utility as a blending grape. It was released in the early 1980s along with two other grape cultivars, Miss Blanc and Miss Blue. It is currently being grown in Mississippi and Texas, but only on a limited scale. In Mississippi the vine is moderately vigorous and productive. It is well adapted to the heat and humidity of the Gulf Coast area. The wine has some susceptibility to anthracnose, black rot, and other fungal diseases, but appears to be highly resistant to Pierce’s disease. MidSouth is highly susceptible to root knot nematodes.